Publications

• Production of biologically active recombinant human factor H in Physcomitrella

  Annette Buettner-Mainik, Juliana Parsons, Hanna Jerome, Andrea Hartmann, Stephanie Lamer, Andreas Schaaf, Andreas Schlosser, Peter F. Zipfel, Ralf Reski and Eva L. Decker, Plant Biotechnology Journal (2010), 1–11

 

• Neueste Strategien in der Krebsimmuntherapie
  Gilbert Gorr, Ralf Kircheis
  Deutsche Zeitschrift für Klinische Forschung (DZKF) 11/12-2007, 33-35 
   
• Proteinherstellung: Bryotechnologie: innovatives Tool für rekombinante Proteinproduktion
  Gilbert Gorr (2007)
  Biospektrum November Ausgabe, 758-760

 

• High-level expression of secreted complex glycosylated recombinant human erythropoietin in the Physcomitrella Delta-fucT Delta-xylT mutant.
  Weise A, Altmann F, Rodriguez-Franco M, Sjoberg ER, Bäumer W, Launhardt H, Kietzmann M, Gorr G.
  Plant Biotechnol J., 2007 May;5(3):389-401
   

• In vivo glyco-engineered antibody with improved lytic potential produced by an innovative non-mammalian expression system.
  Schuster M., Jost W., Mudde GC., Wiederkum S., Schwager C., Janzek E., Altmann F., Stadlmann J., Stemmer C., Gorr G.(2007)
  Biotechnology Journal 2, 700-708.
   
• Compensation of endogenous IgG mediated inhibition of antibody-dependent cellular cytotoxicity by glyco-engineering of therapeutic antibodies.
  Nechansky, A., Schuster, M., Jost, W., Siegl, P., Wiederkum, S., Gorr, G. and Kircheis, R. (2007)
  Molecular Immunology 44, 1826-1828
   
• Glycosylation of recombinant proteins in plants.
  Gorr, G. and Altmann, F. (2006)
  Vol. 2: 345-374. In Medicinal Plant Biotechnology (Eds. Kayser, O. and Quax, W.) Wiley-VCH.
   
• A fast and flexible PEG-mediated transient expression system in plants for high level expression of secreted recombinant proteins.
  Baur, A., Kaufmann, F., Rolli, H., Weise, A., Luethje, R., Berg, B., Braun, M., Baeumer, W., Kietzmann, M., Reski, R. and Gorr, G. (2005)
  Journal of Biotechnology 119, 332-342.
   
• Glycosylation design in transgenic moss for better product efficacy.
  Gorr, G. and Jost, W. (2005)
  Bioprocessing Journal 4, 26-30.
   
• Enhanced recovery of a secreted recombinant human growth factor by stabilising additives and by coexpression of human serum albumin in the moss Physcomitrella patens.
  Baur, A., Reski, R. and Gorr, G. (2005)
  Plant Biotechnology Journal 3, 331-340.
   
• Glyco-engineering of moss lacking plant-specific sugar residues.
  Huether, C.M., Lienhart, O., Baur, A., Stemmer, C., Gorr, G., Reski, R. and Decker, E.L. (2005)
  Plant Biology, 7, 292-299.
   
• Isolation and characterisation of three moss derived beta-tubulin promoters suitable for recombinant expression.
  Jost, W., Link, S., Horstmann, V., Decker, E.L., Reski, R. and Gorr, G. (2005)
  Current Genetics 47, 111-120.
   
• Targeted knockouts of Physcomitrella lacking plant-specific immunogenic N-glycans.
  Koprivova, A., Stemmer, C., Altmann, F., Hoffmann, A., Kopriva, S., Gorr, G., Reski, R., and Decker, E. L. (2004)
  Plant Biotechnology Journal 2, 517-523.
   
• N-Glycosylation in the moss Physcomitrella patens is organized similarly to higher plants.
  Koprivova, A., Altmann, F., Gorr, G., Kopriva, S., Reski, R. and Decker, E.L. (2003)
  Plant Biology 5, 582-591.
   
• Moss – An Innovative Tool for Protein Production.
  Decker, E.L., Gorr, G. and Reski, R. (2003)
  BIOforum Europe 2, 96-97.
   
• Tight control of growth and cell differentiation in photoautotrophically growing moss (Physcomitrella patens) bioreactor cultures.
  Hohe, A., Decker, E.L., Gorr, G., Schween, G. and Reski, R. (2002)
  Plant Cell Reports 20, 1135-1140.