Pharmacokinetics, pharmacodynamics, and safety of moss‐aGalactosidase A in patients with Fabry disease

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Real-Time VCD Monitoring of Moss for Therapeutic Protein Production

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Host Cell Proteome of Physcomitrella patens Harbors Proteases and Protease Inhibitors under Bioproduction Conditions

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Pharmacokinetics, pharmacodynamics, and safety of moss agalactosidase A in patients with Fabry disease

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Molecular Genetics and Metabolism, Volume 123, February 2018, Page S61-S62

Treatment of experimental C3 Glomerulopathy by human complement factor H produced in glycosylation-optimized Physcomitrella patens

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Molecular Immunology, Volume 89, September 2017, Page 120

Moss-produced, glycosylation-optimized human factor H for therapeutic application in complement disorders

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Journal of the American Society of Nephrology 28, 2017

Molecular basis for globotriaosylceramide regulation and enzyme uptake in immortalized aortic endothelial cells from Fabry mice.

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Development of a Novel Host-Cell Protein Assay: Supporting the Physcomitrella patens Expression System

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Biopharmazeutika durch pflanzliche Produktion in geschlossenen Systemen

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Mannose receptor-mediated delivery of moss-made α-galactosidase A efficiently corrects enzyme deficiency in Fabry mice

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Suspension Culture of Plant Cells Under Phototrophic Conditions

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Moss-based production of asialo-erythropoietin devoid of Lewis A and other plant-typical carbohydrate determinants

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Production of biologically active recombinant human factor H in Physcomitrella

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Neueste Strategien in der Krebsimmuntherapie

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Proteinherstellung: Bryotechnologie – innovatives Tool für rekombinante Proteinproduktion

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In vivo glyco-engineered antibody with improved lytic potential produced by an innovative non-mammalian expression system

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Compensation of endogenous IgG mediated inhibition of antibody-dependent cellular cytotoxicity by glyco-engineering of therapeutic antibodies

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Glycosylation design in transgenic moss for better product efficacy

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Enhanced recovery of a secreted recombinant human growth factor by stabilising additives and by coexpression of human serum albumin in the moss Physcomitrella patens

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Glyco-engineering of moss lacking plant-specific sugar residues

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Isolation and characterisation of three moss derived beta-tubulin promoters suitable for recombinant expression

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Targeted knockouts of Physcomitrella lacking plant-specific immunogenic N-glycans

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N-Glycosylation in the moss Physcomitrella patens is organized similarly to higher plants

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Moss – An Innovative Tool for Protein Production

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Tight control of growth and cell differentiation in photoautotrophically growing moss (Physcomitrella patens) bioreactor cultures

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